COTM Reminder is a toolbar for your browser and the best way to remove it is to use ADWCleaner. This application will scan the registry and the files associated with the toolbar and it will remove them with a click of a button. There is no need to use uninstalling methods because it takes care of the problem from its roots.
The application also detects if you have any other bad content installed on your computer and it will provide the means to remove it, if you want.