If you have the To Do List on your Palm, then I recommend deleting the file from your desktop and after this process, restart the Palm Desktop again. The cause to the issue might be related to the missing of the actual database or if the file was stored on a system drive, the software needs administrative rights for it to be opened in the application. Close the application and run it as Administrator. However, if it still does not work with Admin rights, remove the database and the software, re-install it and then sync the Palm with the software.