The software is working just fine on Windows 10. I downloaded version 13 from the official website and installed it. When the software is launched without Administrator access, it will display an error. After installation, right-click the launcher shortcut and choose Run as Administrator. It will give you access to the system partition where it's installed.
Download the software from here: http://www.necpbx.co.uk/downloads/49-applications/81-download-matworx-v13