No, a bootable device cannot be created with CCleaner, but you can use the Portable version to place the application on a USB Flash Drive to run it from that location. Use the link below to download the portable version, then unzip the package to your favorite USB drive. After this procedure, launch the 32bit version or the 64bit version of CCleaner directly from the USB drive without any installation.
Download portable: http://www.piriform.com/ccleaner/download/portable