It's possible that your screen resolution is not enough for the game to run. Try changing it using the Display Settings. Additionally, it's possible that the game uses a resolution higher than your monitor's maximum supported resolution.
According to the official requirements, the game requires OS X 10.6.6 or later to run properly, but given the fact you have the latest version of OSX, that could be a problem if no update is released for the game.
Contact developers: http://www.gamehouse.com/contact