I have always understood Radio-SkyPipe only works on Windows. Now I see it under the Software Informer website as downloadable for Mac. Will it work on a native OS X system or will it require emulation?
This software isn't currently available for Mac computers. You can try to emulate it on a Mac using WineBottler but there might be some incompatibilities. As always, Mac allows you to install Windows through Bootcamp or any other virtualization software available (Parallels Desktop, Vmware Fusion). It's recommended to use Bootcamp to have a native version of Windows running because, sometimes, you might encounter errors during virtualization.