Yes, LabelRIGHT can run with Citizen CL-S631 and all major printers models. All you need to do is to connect your computer and printer to the same network. The software is developed to run on Windows 8, 7, Vista, XP, 2000, NT, ME and 98 platforms and can be acquired from the official web page. Also, you can test it free of charge if you download and install the demo version.