Is it possible with VB 2010 to load multiple images into a single PictureBox (at run time), re-size and arrange them like an album (not layers), and save it all as a single, flat image? Is there a better way to accomplish this?
No. You can't add multiple images into a single PictureBox. In a PictureBox, you can use only one image at a time. If you want to create an album, you can use another program to merge your pictures (you can use Paint or search Software Informer's database for an application that can do that) and afterwards upload the resulted image in the PictureBox.