Even if the size is the same and the HDD uses habitual disk drivers, the answer is no. You cannot use the full size of an HDD to replace your XBOX HDD because the drives are made for custom use. However, most Western Digital drives work normally, but only when they have been customized with a 3rd party tool to enable XBOX storage.
Compatible Western Digital disks:
- WD Scorpio Series BEVS/BEAS
- WD Scorpio Blue Series BEVS/BEVT/BPVT
- WD Scorpio Black Series BEKT/BJKT
- WD VelociRaptor Series
- WD AV-25 Series BUDT