Someone suggested I should explore the PC Studio CD, instead installing from the autorun. With the Windows Explore open, I went to the PC Studio folder and inside found a setupSelector, right clicked and went to PROPERTIES. I changed the compatibility to XP. This got the program to load on Vista. Still this wouldn't find a COM port. So, it still doesn't work. I'm now trying to change every application I can find to be XP compatible to see if that helps. Can you help?