iPhone users who are certainly dependent on iTunes have a way of removing their device from iTunes very easily without stress. There are several reasons why you would want to erase iPhone from iTunes, some of them include: a) change of mobile device; b) privacy concerns.
Step 1 : Open iTunes on your computer and attach your iPhone using the USB cable provided.
Step 2 : Wait for the iPhone's icon to appear in the iTunes interface "Devices" category and click the icon to open your iPhone's summary menu.
Step 3 : Select the “Restore iPhone”.
Step 4 : Click “Restore”. After it finished, you can click “Set up as a new iPhone” to start set up your iPhone.