The The Print Shop Ensemble III is compatible with Windows versions up to Windows 7 (excluded). There have been a lot of reports on the Amazon website with users that complained about compatibility with Windows 7. You can figure it out by yourself that it won't work on Windows 10 regardless of the available options that you have.
However, if you have a powerful PC, you can install VirtualBox and then virtualize Windows XP and continue using the application without any issues.
Note: To virtualize Windows XP you would need the XP Installation Disc or ISO.
