You have to get in touch with the Customer Support to find out what are the system requirements for the HealthPort SmartLink application. I've searched their website but couldn't find anything regarding Windows 10.
Access the following website to get in touch with them. Also, if you have the installation package right click it and choose Properties > Compatibility (tab). Use the drop down menu and choose a previous version of Windows (preferably Windows 7 or Windows XP). Tick the Run as Administrator option as well and then run the program.