Mac Informer keeps you updated in terms of latest articles from the Mac world, latest versions available for your installed applications and much more. If you remove it, you will also lose this functionality and then you'll have to manually update the apps. However, if you continue with the removal process, make sure that the software is not running. Press CMD + ALT + Escape and force close it. Then go to Applications, right click it and send it to Trash. Right click the Trash and empty it.