It's impossible to say if the software is compatible with Windows Vista or not because there is no place to acquire this information from. I checked the official website and a generic page is displayed instead. That page appears when the domain has been discontinued which means the software has been discontinued as well. You can install an alternative called FileZilla. The software supports Windows Vista and newer operating systems as well as 64bit architectures.
Use the following link to reach the download page: https://filezilla-project.org/download.php