No, the software is not compatible with Windows 10 64bit. I have checked their website and these are the operating systems listed in the system requirements section: Windows 7 (32/64 bit), VISTA (32/64 bit) and XP (32/64 bit). As you can see, there is 64bit compatibility, but Windows 10 is missing. If the software requires drives, disable Driver Enforcement and then install them.
Then add a compatibility tweak through Properties > Compatibility for main executable. Choose Windows 7, tick the Run as Administrator and the launch the application.
For additional info, contact the developers: http://www.soundgraph.com/imon-manager-feature-en/