I'm using Windows 10 which as a standard has no template for 10 labels per sheet. Will your downloadable program be compatible with Windows 10? Does it contain a template for 10 labels per sheet such as Avery 5163,8163 or 8463?
I have checked what you've said, and Windows 10, doesn't have the default setting of 10 labels per sheet. You need the actual template to be downloaded and installed on your computer. For example, the Avery website provides users with a template that's compatible with the numbers you have specified above. Use that to overcome the issue with Windows 10.
Avery website: http://www.avery.com/avery/en_us/Templates-%26-Software/Templates/Labels/Shipping-Labels/Shipping-Label-10-per-sheet-_Adobe-InDesign.htm