There isn't much information about the supported applications, but according to the official website, Simple EMR is compatible with National Drug database. It's possible to have multi-users over the network (admin, normal user). This is possible due to the multi-user feature available within the application. The software requires Windows 7 OS or newer to run properly and Net Framework 3.5. No, the software doesn't come with its own Help or help documents. I have installed the software but no help was available. The database used is in MDB form which means it can be accessed with the help of Microsoft Access. The support can be established via the Contact page. There is no support page, because the help is provided through email.