The "Instrument Toolkit" program may not be working in Windows 11 due to compatibility issues. Windows 11 has different system requirements and architecture changes compared to previous versions, which might affect the functionality of some older applications. It's advisable to check for any software updates from the developer that specifically address Windows 11 compatibility, or look for any patches or troubleshooting steps that they may have provided. Additionally, running the program in compatibility mode for an earlier version of Windows may also help.