The procedure for setting up handicaps for a group of 25 players differs depending on the specific software being used. In Golf Digest, it is recommended to create a handicap league within the program and then add all 25 players to the league. Once the league is created, the software will automatically calculate and update handicaps for each player based on their performance in league play. More specific instructions can be found in the Golf Digest software user manual or by contacting their customer support team.