No, ImageMixer 3.14 is not compatible with the Windows 10 operating system. According to the system requirements found on various websites, you can install ImageMixer 3.14 on Windows 98, NT, 2K, ME, XP, 95, and Windows Vista.
If you still have the installation package you could try to run it, but I doubt it would run even you apply a compatibility tweak for the main package.