This is a compatibility issue which means the software's code hasn't been adjusted to work on higher versions of Windows (eg. Windows 10). If compatibility tweaks didn't work, then you will need a new and updated version that is Windows 10 compatible, or you could install Windows 7 or XP through virtualization and then play the game.
For virtualization, you could use VirtualBox: https://www.virtualbox.org/
I've also checked the developer's website and it appears that the game has been discontinued starting this year.