If I write in English, will this software translate it into Oriya?
No, the software doesn't offer language translation. This is more of a keyboard layout. You can configure it to display a window with the keyboard where each English letter corresponds to the Oriya letter as well. I've checked the description and the software and it doesn't offer translation support.
You can use the user guide hosted on ScribD to learn about the software: https://www.scribd.com/doc/4028086/Akruti-Marathi-MultiFont-Engine-Readme