According to system requirements, this game will run perfectly fine on Windows XP or Vista. There is no Windows 10 mentioned, which means that you can't play it on Windows 10, officially. Since there is the possibility of downloading it on your computer, the next thing to do is to test it by yourself. If you already upgraded to Windows 10, download the game and install it. Make sure to use Run as Administrator in Windows 10.
Download game: http://www.wildtangent.com/games/alchemy-deluxe