Firstly, make sure that your computer meets the minimum system requirements to run NBA 2K13:
- CPU: Pentium 4 with 2.4 Ghz Single Core processor or equivalent (2.8 Ghz for Vista/Win 7);
- RAM: 512 MB or more (1 GB for Vista/Win 7);
- OS: Windows XP;
- Video Card: Nvidia Geforce 6800 or ATI Radeon HD 2400.
If all the requirements are fulfilled, I recommend uninstalling the game from your PC (Control Panel > Uninstall a program) and then downloading and running a registry cleaner from Software Informer database to make sure that there are no leftover registry keys in your system. After that, reboot the PC and install the game again. Also, I recommend that you update DirectX to the latest version.