Yes, you have the possibility to write ISO/bootable images directly to the USB stick. To do this, open the application then go to File > OPen. Choose the image and then access Bootable > Write disk image. Choose the DISK, then select USB-HDD+ > Format > Write. Depending on the ISO image, the process might take a while.
After it's finished, reboot the PC, press the Boot Selection Key then go to HDD > USB Stick's NAME.