In order to remove an application from your computer, you can choose between two methods. The classic and the most known method is: go to Control Panel > Uninstall a program > search Microsoft SkyDrive and hit uninstall. Another method to remove a program from your system is to use an uninstalling tool like: Revo Uninstaller. These uninstalling tools not only remove your software form your system, but, also clean up your computer registry.