The Smart Cyclic Redundancy Check Fixer Pro software comes with 4 scanning modules: Registry Cleaner, Evidence Cleaner, Junk File Cleaner, and Shortcuts Cleaner.
Unfortunately, only Junk File Cleaner and Shortcuts Cleaner will allow you to scan a specific location. The first two modules will scan the entire computer. If you want to scan the F drive using Junk File Cleaner or Shortcuts Cleaner, open one of them, check the box next to F drive, and press Scan. However, in order to fix your external drive problems, I recommend that you try Hard Disk Sentinel software.