That happens because the exPressit application wasn't developed for the Windows 7 operating system. If I recall correctly, exPressit is actually an old application that is compatible with versions of Windows up to Windows XP.
Therefore either apply a compatibility tweak for the main executable using right-click on the file then Properties > Compatibility. Choose Windows XP from the list and check the Run as Administrator option.
Additionally, if you have a fast and modern computer, install VirtualBox and configure it to run Windows XP. Transfer the Memorex exPressit Label Design Studio in that environment and you'll have the possibility to run it this way.