Every app is different and works in its own way and In-Synch RMS doesn't get too far from that "rule". However, I checked their website and found a few images with the interface of the software. From what I see, there is the SAVE icon present at all times. If you add something, simply press save, close and then you can get back and continue your work. Unfortunately, I can't download the software to test it out since it's not available for public downloading.
Drop them an email to ask about this inquiry if you are not sure how the software works: http://www.in-synchrms.com/contact-us