It's impossible to say if the program will work on a Mac or not since there is no information about it. I've searched on the official website, but nothing could be found in terms of software availability, system requirements, troubleshooting or support. Because of that you will have to get in touch with the developers to find more about it.
Alternatively, use Wine Bottler if you already have the setup package for PortWise Access Client.
Note: Wine Bottler makes it easy to run Windows apps on a Mac OSX.