No, the software is not compatible with a Windows x64 machine. According to the system requirements presented in the brochure, the software will work on the following versions of Windows: Windows 2000, XP and Vista.
You can download the brochure by yourself using the following link: http://download.schneider-electric.com/files?p_enDocType=Brochure&p_File_Id=683081495&p_File_Name=MiCOM+S1+Studio.pdf&p_Reference=MiCOM%2BS1%2BStudio
Additionally, if you have the setup package, right-click it and choose Properties > Compatibility. Select one of the versions listed above and then run it.