No, the application is not compatible with Cricut Express 2 or any other Cricut version. According to the official website, you can use the application with the following products:
Black Cat Cougar/Lynx
BossKut Gazelle
Craftwell eCraft
CraftRobo/Graphtec
GCC
Foison
Liyu
Pazzles Inspiration/Pro
Ramtin
Roland
Seiki
Silhouette SD/CAMEO/Portrait
Silver Bullet
USCutter Copam/LaserPoint/MH/PCUT/SC/TC
Vinyl Express
Wishblade
